Intern, Pharmaceutical Engineering, Drug Product, PDM at Revolution Medicines

Ideal for a student working towards a BS, MS, or PhD in Chemical Engineering, Pharmaceutical Sciences, or a related field, this role offers hands-on engineering

Work type: hybrid

Location: Redwood City, California, United States

Salary: $67,000 – $81,000/yr

Type: Full-time

Summary

Ideal for a student working towards a BS, MS, or PhD in Chemical Engineering, Pharmaceutical Sciences, or a related field, this role offers hands-on engineering support. **What makes it worth a look...** This full-time, hybrid internship at Revolution Medicines in Redwood City, California, offers a salary between $67,000 and $81,000 annually. **You might be a good fit if you...** * Are working towards a BS, MS, or PhD in Chemical Engineering, Pharmaceutical Sciences, or a related discipline. * Can support clinical-stage and late-stage process development using principles of Quality by Design (QbD), OFAT, and DOE. * Have experience with statistical analysis software like JMP or can quickly learn it. * Possess strong organizational skills and attention to detail for managing experimental data.

Job Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Playing an important role as engineering support within the Drug Product team, and working closely with Scientsts and Process Engineers within the group. A successful candidate will be responsible for supporting clinical-stage and late-stage process developments as well as supporting preparation for Process Performance Qualification of Revolution Medicines’ compounds.

• Work closely with Scientists and Process Engineers within Drug Product group to support the transition of drug product manufacturing from clinical stage development through late stage development and Process Performance Qualification (PPQ).

• Support formulation and process development and optimization studies conducted according to the principles of Quality by Design (QbD), using tools such as OFAT (one factor at a time) experiments and DOE (Design of Experiments).

• Review protocols, manufacturing batch records, and development, campaign, and technical reports for clinical-stage and late-stage manufacturing.

• Analyze data and perform statistical analysis to support process development and optimiziation, process capability, and process range justification.

• Build and maintain databases to manage and track experimental data and results for multiple Programs.

• Conduct literature reviews and stay updated on the latest advancements in drug product development and manufacturing.

• Working towards a BS or MS or Ph. D in Chemical Engineering, Pharmacetuical Sciences, or related discipline.

• Strong problem-solving skills with sound technically driven decision-making ability.

• Effective written and verbal communication skills and interpersonal skills.

• Ability to review and interpret technical documents and protocols.

• Strong organizational skills and attention to detail.

• Ability to work collaboratively in a team environment.

• Familiarity with regulatory requirements and guidelines in the pharmaceutical industry.

• Knowledge of Quality by Design (QbD) principles and tools such as OFAT and DOE a plus.

• Proficiency in statistical analysis software (JMP) a plus.

The base pay salary range for this intern position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

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