Intern, Structural Biology at Revolution Medicines

Ideal for an undergraduate with biochemistry lab experience, particularly coursework or research, who has completed organic chemistry and is familiar with small

Work type: onsite

Location: Redwood City, California, United States

Salary: $67,000 – $81,000/yr

Type: Full-time

Summary

Ideal for an undergraduate with biochemistry lab experience, particularly coursework or research, who has completed organic chemistry and is familiar with small molecule structures. **What makes it worth a look...** This is a full-time, on-site summer internship at Revolution Medicines in Redwood City, California, offering a salary range of $67,000 - $81,000 per year. **You might be a good fit if you...** * Have experience with protein handling, characterization, and storage using techniques like FPLC or HPLC. * Are familiar with protein quantitation methods such as Bradford and Nanodrop. * Possess experience with protein purification and wetlab structural biology techniques.

Job Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

We are looking for a summer intern to join the Structural Biology team and support multiple oncology therapeutic programs. Working from the bench, they will hone their skills in protein purification, production and harvesting of protein-small molecule co-crystals, and other core structural biology wetlab and computational techniques.

Required Skills, Experience and Education:

Undergraduate biochemistry lab experience, either coursework or research under the supervision of graduate student/professor

Completion of organic chemistry and familiarity with small molecule representations and functional groups

Experience with protein handling, characterization, and storage (FPLC or HPLC techniques like SEC and affinity chromatography. PAGE, quantitation via Bradford and nanodrop etc.).

Excellent written and verbal communication skills.

Enthusiasm to work hard and learn this summer!

Preferred Skills:

Experience with growing and harvesting protein crystals highly desirable.

Prior use of crystallographic software suites (CCP4, Phenix) and visualization software (PyMOL, Chimera) also highly desirable. #DNI

The base pay salary range for this intern position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

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