Senior Director, Epidemiology at Revolution Medicines

You're a seasoned epidemiologist with a PhD or equivalent and at least 12 years of industry experience, specifically in oncology. **What makes it worth a look.

Work type: remote

Location: Remote (United States)

Salary: $244,000 – $305,000/yr

Type: Full-time

Summary

You're a seasoned epidemiologist with a PhD or equivalent and at least 12 years of industry experience, specifically in oncology. **What makes it worth a look...** Revolution Medicines, a late-stage clinical oncology company, is offering a fully remote Senior Director, Epidemiology role in the United States with a salary of $244,000 - $305,000 per year. **You might be a good fit if you...** * Possess a PhD/DSc/DrPH in epidemiology or a related advanced science degree. * Have a strong technical understanding of pharmacoepidemiologic methods and real-world oncology data. * Can demonstrate a history of publications showing successful epidemiologic research. * Are knowledgeable about the drug and clinical development process for targeted medicines.

Job Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Director, Epidemiology is responsible for leading the strategy and execution of epidemiology plans and activities for Revolution Medicines assets and/or indications. They will be accountable for working across the clinical development, safety, medical affairs, and commercial matrix developing strategies and overseeing execution of key epidemiology deliverables. Reporting to the Executive Director, Head of Epidemiology, they will closely align with the Global Patient Safety organization to provide epidemiologic context to potential safety signals, inform the benefit/risk of Rev Med products, and contribute to the design and execution of post-approval safety studies, globally. This is an exceptional opportunity to contribute to the advancement of oncology by generating innovative real-world evidence that will shape the future of patient care.

• The Senior Director, Epidemiology will lead the epidemiology strategy for a given asset and/or indication, including developing plans for epidemiology deliverables (e.g., systematic literature reviews, natural history studies, clinical trial design and optimization, comparative effectiveness and safety, post-approval safety studies, and healthcare resource utilization analyses).

• Designs and executes deliverables in accordance with the plan, either personally or through oversight of other epidemiologists/vendors/contractors; this may involve the development of templates and SOPs, as well as authoring protocols, SAPs, clinical study reports, slide decks, abstracts, posters, and peer-reviewed manuscripts.

• Provides epidemiology leadership to Clinical Development, Global Patient Safety, Regulatory Affairs, Medical Affairs, and Commercial activities across the medicines development life cycle. Active participation on cross-functional teams. Lead sub-team meetings as appropriate.

• Ensures epidemiology point of view is included in key deliverables from other functions such as clinical trial protocols, SAPs, case report forms, regulatory submissions and payer interactions within assigned indications and/or therapeutic areas.

• Lead activities related to scientific manuscripts, clinical conference abstracts, presentations, and posters based on observational study data.

• Represents HEOR/RWE department during interactions with key external stakeholders including Scientific Advisory Boards and regulatory authorities.

• Appraises and synthesizes relevant epidemiological and RWE literature and regulatory guidance documents.

• PhD / DSc / DrPH in epidemiology or a relevant advanced science degree with and at least 12 years of related industry experience at a sponsor/pharmaceutical company.

• Demonstrated technical knowledge of pharmacoepidemiologic methods and real-world oncology data sets as well as the use of appropriate biostatistical methods.

• History of publications demonstrating the successful design, execution and communication of epidemiologic research.

• Knowledge of drug and clinical development process for genomic/targeted medicines.

• Excellent analytic and problem-solving skills.

• Excellent attention to detail and quality, and scientific rigor.

• Strong interpersonal skills and the ability to work effectively in multidisciplinary teams, including ability to provide oversight to vendors.

• Existing external relationships to foster collaborative and timely research.

• 12+ years of oncology pharmacoepidemiology experience at a sponsor/pharmaceutical company.

• Experience driving from conception to completion post-approval safety studies using RWD submitted to global regulators.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

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