Senior Director, Real World Data & Analytics at Revolution Medicines

You're an experienced PhD or equivalent with at least 12 years in real-world data analytics and evidence generation within pharma or biotech, looking to build a

Work type: remote

Location: Remote (United States)

Salary: $244,000 – $305,000/yr

Type: Full-time

Summary

You're an experienced PhD or equivalent with at least 12 years in real-world data analytics and evidence generation within pharma or biotech, looking to build and lead a new group. **What makes it worth a look...** Revolution Medicines is offering a Senior Director, Real World Data & Analytics role with a salary range of USD 244,000 - 305,000 per year, fully remote within the United States. This is a chance to establish and scale a new RWD&A group within a late-stage clinical oncology company. **You might be a good fit if you...** * Hold a PhD, DSc, or DrPH in epidemiology or biostatistics, or a related advanced science degree. * Have strong expertise with RWD sources like claims, EHR, registries, and -omics data, and analytic tools R, SAS, or Python. * Possess demonstrated experience leading complex RWD/RWE projects from inception through reporting and submission. * Can provide thought leadership in advanced analytic techniques such as causal inference and AI/ML.

Job Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Director, Real-World Data & Analytics will work with the Executive Director, Head of Epidemiology and VP of HEOR to establish the RWD&A group at RevMed, scaling organizational capabilities and leading the strategy and execution of key RWD&A deliverables for RevMed assets. They will be accountable for working across the clinical development, safety, medical affairs, commercial including analytics and insights, and IT matrix, developing strategies and leading and/or overseeing execution of key projects. Reporting to the Executive Director, Head of Epidemiology & RWD Strategy, they will closely align with the other users of RWD at RevMed, develop ways of working and communication channels to maximize RevMed’s investment in RWD as well as lead the analysis (either directly or leveraging junior team members and vendors) of RWD database and other studies. This is an exceptional opportunity to contribute to the advancement of oncology by leveraging real-world data and analytics that will shape the future of patient care.

• Develop and lead RWD and analytics plans to support portfolio, Medical Affairs, HEOR/RWE, and epidemiology goals.

• Provide subject matter expertise on RWD data sources, their strengths/limitations, and the feasibility of answering key scientific questions using available data.

• Oversee high-quality RWE study design, protocol development, statistical analysis planning, and final reporting in support of regulatory submissions and product value evidence – typical projects include include systematic literature reviews, natural history studies, clinical trial design and optimization, comparative effectiveness and safety, and healthcare resource utilization types of studies, post-approval safety studies leveraging RWD, as well as RWD-related insights such as quick feasibility and information used to inform our fast-moving clinical programs.

• Ensure fit-for-purpose methods are used to provide scientific rigor to non-interventional studies so that they adhere to global regulatory guidance frameworks and are acceptable to other key stakeholders.

• Provide thought leadership in advanced analytic techniques (e.g., causal inference, predictive modeling, AI/ML) that reflect current industry practices.

• Communicate insights and analysis effectively to senior stakeholders, regulatory agencies, payers, and scientific audiences through written reports and presentations.

• Participate in governance, feasibility review, and multidisciplinary project teams, ensuring RWD analytics add meaningful insight at key decision points.

• Build, mentor, and lead a high-performing analytics team with expertise in epidemiology, biostatistics, data science, and RWE methodologies.

• Drive adoption of robust analytics standards and tools that enhance consistency and scalability of RWD efforts across projects including partnership with other functions to establish data ingestion pipelines, and support the establishment of data lakes.

• PhD / DSc / DrPH in epidemiology or biostatistics, or a relevant advanced science degree and at least 12 years of experience with RWD analytics and evidence generation in pharma/biotech.

• Demonstrated experience leading complex RWD/RWE projects from concept through delivery, including study design, analysis, and reporting/submission to regulatory agencies.

• Strong expertise with RWD sources (claims, EHR, registries, -omics data, linked datasets) and analytic tools (R/SAS/Python).

• Demonstrated technical knowledge of epidemiologic, biostatistical, and data science methods.

• Knowledge of drug and clinical development process for genomic/targeted medicines.

• Excellent analytic and problem-solving skills.

• Strong interpersonal skills and the ability to work effectively in multidisciplinary teams, including ability to provide oversight to vendors.

• Experience in oncology RWD&A.

• Track record of publications or presentations in RWD&A/epidemiology/data science.

• Experience aligning RWE strategy to regulatory and payer evidence planning, especially around the planning and execution of post-approval safety studies.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

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