Senior Scientist I, Clinical Biomarker Development at Revolution Medicines

You're a scientist with a PhD and at least three years of industry experience in clinical biomarkers or translational medicine. You’ve supported oncology clinic

Work type: hybrid

Location: Redwood City, California, United States

Salary: $149,000 – $186,000/yr

Type: Full-time

Summary

You're a scientist with a PhD and at least three years of industry experience in clinical biomarkers or translational medicine. You’ve supported oncology clinical trials and are comfortable with genomic and proteomic assays. **What makes it worth a look...** Revolution Medicines is offering a hybrid Senior Scientist I role in Redwood City, California, with a salary of USD 149,000 - 186,000 per year. **You might be a good fit if you...** * Have experience supporting oncology clinical trials with biomarker components. * Are familiar with genomic/molecular and proteomic assays. * Have experience managing external vendors and CROs. * Can translate preclinical findings into clinical biomarker hypotheses.

Job Description

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Scientist I in Clinical Biomarker Development team, within the Translational Medicine will play a key role in the design, execution, and interpretation of clinical biomarker strategies across Revolution Medicine’s oncology pipeline. You will:

• Design and execute clinical biomarker strategies to support early response monitoring, patient stratification, and understanding resistance mechanisms.

• Support biomarker implementation for early- and late-stage oncology clinical trials.

• Oversee biomarker assay development, qualification, and sample analysis in collaboration with internal teams and external CROs.

• Analyze and interpret biomarker data in the context of clinical outcomes and present results to cross-functional teams.

• Contribute to clinical protocols, study reports, and regulatory documents (e.g., INDs, IBs, CSRs).

• Translate preclinical findings into clinically actionable biomarker hypotheses.

• Stay current with emerging biomarker technologies and trends in precision oncology.

• PhD in a relevant scientific discipline with 3+ years of relevant industry experience in clinical biomarkers, translational medicine, or related roles.

• Experience supporting oncology clinical trials with biomarker components.

• Familiarity with biomarker platforms such as genomic/molecular and proteomic assays.

• Experience working with CROs and managing external vendors.

• Strong scientific communication skills and ability to work cross-functionally.

• Experience with targeted oncology therapies or RAS/MAPK pathway biology.

• Biological understanding of pancreatic, non small cell lung and/or colorectal cancers is preferred.

• Familiarity with analytical software for data anlaysis and interpretation.

The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

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